New clinical study ny Dr Yoram Harth et. al. show that the tested electronically controlled motorized insertion, non- insulated microneedle treatment technology provides a minimal discomfort, minimal downtime, effective and safe treatment for depressed acne scars
Depressed Acne Scars—Effective, Minimal Downtime Treatment with a Novel Smooth Motion Non-Insulated Microneedle Radiofrequency Technology
Background: The microneedle fractional RF handpiece used in our study (Intensif Handpiece, EndyMed Medical, Caesarea, Israel) is a novel handpiece that uses a tip with 25 non-insulated, gold plated microneedle electrodes. The needles are inserted into the skin by a specially designed elec- tronically controlled, smooth motion motor minimizing patient discomfort. RF emission delivered over the whole dermal portion of the needle allows effective coagulation resulting in minimal or no bleeding, together with bulk volumetric heating. Study Design/Materials and Methods: The study included 20 patients, treated for depressed acne scars using the IntensifTM Microneedles handpiece (EndyMed PRO Platform System, EndyMed Medical, Caesarea, Israel). The degree of clinical improvement was assessed by the global aesthetic improvement scale (GAIS) and subjects satisfaction by post treatment questionnaires. Results: The number of treatments per patient va- ried between 1 and 6 (average 3.3 treatments per patient). Eleven patients (55%) reported none to minimal pain, six (30%) moderate discomfort and only three (15%) reported significant pain. Objective evaluation of the improvement by a board certified dermatologist showed improvement in 95% of patients. 25% showed excellent improvement, 50% experienced good improvement, and the 20% showed minimal improvement. One patient showed no improvement. Conclusions: The presented results show that the tested electronically controlled motorized insertion, non- insulated microneedle treatment technology provides a minimal discomfort, minimal downtime, effective and safe treatment for depressed acne scars.
J Dermatol Sci. 2002 Nov;30(2):129-35.
Acne phototherapy with a high-intensity, enhanced, narrow-band, blue light source: an open study and in vitro investigation.
Department of Dermatology, Kinki University School of Medicine, Ohno-Higashi 377-2, Osaka-Sayama city, Osaka 589-8511, Japan. email@example.com
The purpose of this study was to investigate the efficacy of phototherapy with a newly-developed high-intensity, enhanced, narrow-band, blue light source in patients with mild to moderate acne. An open study was performed in acne patients who were treated twice a week up to 5 weeks. Acne lesions were reduced by 64%. Two patients experienced dryness. No patient discontinued treatment due to adverse effects. In vitro investigation revealed that irradiation from this light source reduced the number of Propionibacterium acnes (P. acnes), but not Staphylococcus epidermidis that were isolated from the acne patients. Phototherapy using this blue light source was effective and well tolerated in acne patients and had an ability to decrease numbers of P. acnes in vitro, suggesting that this phototherapy may be a new modality for the treatment of acne.
J Cosmet Dermatol. 2008 Sep;7(3):180-8.
An assessment of the efficacy of blue light phototherapy in the treatment of acne vulgaris.
Cardiff University, Cardiff, UK. firstname.lastname@example.org
Acne vulgaris is a common skin condition that affects 8 out of 10 people. It varies from mild to severe, and different treatments target various aspects of the disease. Propionibacterium acnes, one of the culprits involved in the pathogenesis of acne vulgaris, is the main target of all major medical treatments used. Studies conducted in recent years have shown favorable effects within the visible light spectrum for the treatment of acne vulgaris.
In this study, we have evaluated the use of intense blue light within the spectral range of 415-425 nm (peak 420 nm) in the treatment of acne vulgaris.
Twenty-one patients with mild to moderate facial acne were treated with blue light phototherapy. All patients were given 14-min treatment sessions twice a week for 4 weeks. Acne severity was assessed using the Leeds Technique for grading and lesion counts. Disability was assessed using the Dermatology Life Quality Index (DLQI). In addition, standard digital and cross-polarized light photographs were taken and graded by a blinded evaluator. Visual analog scale (VAS) scores and cultures for P. acnes were carried out before starting the treatment and upon completion of the treatment.
Significant improvement was achieved in the Leeds Acne Grade (P = 0.001). The inflammatory (P = 0.001) and noninflammatory (P = 0.06) lesion counts also improved significantly. A similar change was noted in the DLQI (P = 0.001); a degree of significance was also achieved in the patients’ and the investigators’ VAS scores (P = 0.01 and P = 0.001, respectively). P. acnes colony counts failed to show a significant decrease at the end of the treatment and remained almost constant (P = 0.660).
We believe that blue light does appear to have some role in the management of acne and may be beneficial for the treatment of a select group of mild to moderate acne patients.
J Cosmet Laser Ther. 2003 Jun;5(2):111-7.
The effective treatment of acne vulgaris by a high-intensity, narrow band 405-420 nm light source.
Beit Harofim Holon, Israel.
Available topical treatments are slow and frequently irritating. Oral therapies may be associated with increased bacterial resistance (antibiotics) or possible severe side effects (oral isotretinoin). In vitro and in vivo exposure of acne bacteria to 405-420 nm ultraviolet (UV) free blue light results in the photo-destruction of these bacteria through the effects on the porphyrins produced naturally by Propionibacterium acnes. A novel, high-intensity, narrow band 420 nm UV free blue light has been shown to decrease inflammatory acne lesions after eight bi-weekly treatments.
To examine the effects of high-intensity, narrow band 420 nm UV free blue light (ClearLight) on inflammatory acne lesions.
Three studies were carried out to examine the clinical effects of high-intensity, narrow band blue light on papulo-pustular acne: the split-face dose-response study, the full-face open trial and the split-face, double-blind controlled study. The studies enrolled 10, 13 and 23 patients respectively.
The data show more than an 80% response to 420 nm acne phototherapy with a significant reduction of 59-67% of inflammatory acne lesions after only eight treatments of 8-15 minutes. The reduction in lesions was steady in the follow-ups at 2, 4 and 8 weeks after the end of therapy. Prolonged remission was evident in the 8 weeks after the end of therapy. No adverse effects or patient discomfort were noted in any of the patients.
Acne phototherapy by high intensity, narrow band 405-420 nm light is proven to be an attractive, fast, effective, non-invasive alternative to current topical and parenteral anti-acne remedies.Share on Facebook
Read some of the recent readers reviews:
Review by: Matt Kelland on June 01, 2012 :
Acne affects almost everyone – 85% of people will suffer from it at some point in their lives, whether in their teenage years or later. This simple, easy to read book does four things really well. First, it explains what acne is and why you get it. Second, it dispels some of the common myths about acne. Third, it outlines the common treatments available, whether they’re home remedies, OTC medicines, or require medical assistance.
Fourth, and perhaps most important, it gives you a useful list of simple do’s and don’ts. I didn’t know, for example, that shaving in two directions can break the hairs and cause a spot, or that leaving the shaving gel on for a few minutes before shaving reduces the chances of folliculitis. Even changing your toothpaste can reduce the severity of acne.
(reviewed the day of purchase)
Review by: Danielle Christine on May 21, 2012 :
I bought this book for my teenage daughter. It is a very clearly written guide on acne and its treatment. It not only describes different methods on how to treat pimples but also goes over some common myths and tips, including info about your skin and what causes acne. I was pleased with the book and would recommend it to anyone who suffers from acne.
(reviewed within a week of purchase)
Review by: MP Publishing on May 21, 2012 :
This guide is for anyone – teen or adult – who suffers from acne and needs help to get clear skin. It really helped me understand what causes acne and what makes it worse. You will also get a very thorough descriptions on different treatment methods from soaps and creams to antibiotics and other medications such as accutane. Very easy to read guide written by a dermatologist that goes to the point and does not contain any nonsense.
(reviewed within a week of purchase)
Review by: Jeniffer on March 30, 2012 : (no rating)
I had 2 kids with acne. This book helped me a lot to understand the causes of the problem. The tips in the book are clear and super usefull. Uptodate, Clear, concise and absolutely non comercial. I finally know what to do. Highly recommended to anyone with Acne or Acne in the family.
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The adult acne can be divided into a few groups.
Acne after adolescence:
Statistics show that up to 25% will suffer from acne breakouts after the age of 20. This type is different than the regular adolescent acne :
People (mostly women) older than 20 that continue have acne breakouts. This type is more common in females and may continue to the age of 30, 40 and evan 45. included in this type are women, that have acne flare ups during pregnancy. This type of acne is usually worse during the first trimester of pregnancy when levels of progesterone are highest.
Folliculitis : Man in this age may have pimples/bumps in their beard area called folliculitis . Folliculitis is caused by an infection around the hair follicle – usually by a bacteria called Staph Aureus.
Acne due to hormonal imbalance:
Rare cases of acne can be induced by high level of hormones with testosterone like activity. This includes polycystic ovary syndrome , internal diseases/tumor that causes the body to ver produces, or external ingestion of hormones such as the steroids used by professional body builders.
|Before 20||After 20|
|Area||Nose, Forehead, Chin, Cheeks||Around the mouth, lower cheeks, under the jaws|
|Scarring||May be severe||Usually less or no scarring|
Treatment of post adolescent acne
First step would be to rule out hormonal imbalance, This can be done easily through a couple of blood tests.
Once the blood tests are normal – attention should be placed on cosmetics used. Everything used should be Oil free and non comedogenic.
Medications should be chosen according to the severity, starting with simple non drying topical antibiotics , combined with low percentage of benzyl peroxide, or in milder cases azelaic acid creams. In more severe cases a course of oral antibiotics may be very helpful followed by a followup prevention plan (The right cleanser and mild acne acne topical will be needed long term.) .
In the most severe cases that experience multiple relapses after antibiotics, low dose accutane combined with simultaneous blue light phototherapy will be the ideal choice.
Birth control pills for acne ?
Birth control pills are not a treatment for acne. The estrogens in the pill suppress the levels of testosterone in the circulation , decreasing its effect on the sebaceous gland and by that decreasing sebaceous gland enlargement and sebum secretion. These should be taken only if the women is sexually active. The pills may calm acne breakouts but a rapid relapse is expected when they are stopped. The best pills for acne will be the one that have minimal androgenic (testosterone like) effect . Examples will be Seasonale, Desogen, levlen. Two types of birth control pills have useful non hormonal ingredients that can further reduce the hormonal trigger of acne. Jasmin contains a non hormonal compund similar to spironolactone t and Diane (approved in Europe) a chemical called cyproterone both directely suppress androgen activity.
For the right contraceptive pill consult your Gynecologist…
Research conducted primitive tribes in Southeast Asia showed that teenagers fed on a basic diet of meat and grain gathered in nature almost never suffer from acne. It seems that sugar, white flour and cow milk are among the factors that can exacerbate acne. It is well known salt contains small amounts of iodine. Since iodine is one of the factors known to worsening acne Yishai claim should reduce the eating of very salty foods.
Eliminate: food that contains lots of sugar, cakes, sweets and ice cream. The worst are baked goods like cookies and white flour,,
white bread and other sweets.
Eliminate sugary drinks, cola and fruit juices. You should switch to drinking water,
herbal teas and drinks with artificial sweeteners.
Eliminate eating nuts. Nuts contain a large amount of fat in addition to large amount of salt.
Eliminate as much as possible cow milk. . Most of the cows that give us milk , are pregnant during milking. The milk of these cows contain a large amount of progesterone like hormones. These hormones have a Dihydroxy testosterone (DHT) activity that makes acne worse.
A study of 47 thousand women (!) In the U.S. showed that women who drank more than two glasses of milk a week was 44 percent more risk of getting acne than women who drank one glass of milk or less. Not found substantial difference between regular or skim milk. It is believed that unsweetened soy milk can be a good replacement. It was also found that women who reported eating more than her day of cottage cheese, cheese spreads over 30% fat, milk-based drinks being teenagers – had more severe acne. (The risk was 63 percent higher than for the women who reduced these foods).
It is dvised to avoid large quantities of vitamin B6 and B12. Using large amounts of both these vitamins
have been shown in some cases to cause worsening of acne.
What you should eat?
It is advised to eat more fish (salmon, tuna, sardines). These fish contain such important fatty acids Omega-3 may also benefit the skin and overall health. It s also possible to take capsules containing these acids (fish oil).
It is recommended to drink plenty of water. You should start the day drinking water and continue to drink
at least 8 cups of additional water during the day.
Is chocolate bad for your acne?
Cocoa itself does not make acne worse. Nevertheless the sugar and milk in it can.
If you want chocolate, look for low sugar chocolate containing a high percentage of cocoa (70%).